Anti-PHOX2BPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-PHOX2B Polyclonal Antibody品牌:solarbio | 货号:K006047P

英文名称Anti-PHOX2B Polyclonal Antibody
宿主Rabbit
别名NBLST2;NBPhox;PMX2B
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量32kDa
Gene ID8929
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human PHOX2B
性状液体
Public Immunogen RangeRecombinant protein of human PHOX2B
Subcellular LocationsNucleus
Swiss ProtQ99453
克隆类型 Polyclonal Antibody
背景资料The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.

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