Anti-OPTNPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-OPTN Polyclonal Antibody品牌:solarbio | 货号:K007148P

英文名称Anti-OPTN Polyclonal Antibody
宿主Rabbit
别名NRP;FIP2;HIP7;HYPL;ALS12;GLC1E;TFIIIA-INTP
应用IHC
稀释比例IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量66kDa
Gene ID10133
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human OPTN
性状液体
Public Immunogen RangeRecombinant protein of human OPTN
Subcellular LocationsCytoplasm
Swiss ProtQ96CV9
克隆类型 Polyclonal Antibody
背景资料This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

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