Anti-APAF1PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-APAF1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-APAF1 Polyclonal Antibody品牌：solarbio | 货号：K007367P

英文名称	Anti-APAF1 Polyclonal Antibody
宿主	Rabbit
别名	CED4
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	142kDa
Gene ID	317
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human APAF1
性状	液体
Public Immunogen Range	A synthetic peptide of human APAF1
Subcellular Locations	Cytoplasm
Swiss Prot	O14727
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.

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