Anti-GRM3PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-GRM3 Polyclonal Antibody品牌:solarbio | 货号:K007505P

英文名称Anti-GRM3 Polyclonal Antibody
宿主Rabbit
别名GLUR3;mGlu3;GPRC1C;MGLUR3
应用WB
稀释比例WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量99kDa
Gene ID2913
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human GRM3
性状液体
Public Immunogen RangeA synthetic peptide of human GRM3
Swiss ProtQ14832
克隆类型 Polyclonal Antibody
背景资料L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

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