Anti-ABCB11PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ABCB11 Polyclonal Antibody品牌:solarbio | 货号:K007568P

英文名称Anti-ABCB11 Polyclonal Antibody
宿主Rabbit
别名BSEP;PGY4;SPGP;ABC16;BRIC2;PFIC2;PFIC-2
应用IHC
稀释比例IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量146kDa
Gene ID8647
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ABCB11
性状液体
Public Immunogen RangeA synthetic peptide of human ABCB11
Subcellular LocationsCytoplasm
Swiss ProtO95342
克隆类型 Polyclonal Antibody
背景资料The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

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