产品详情

产品编号：AF-200-05

产品描述：

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 are cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

Manufactured using all Animal-Free reagents.

Source:E.coli

Synonyms:Interleukin-5, EDF, BCDFII, TRF

AA Sequence (monomer):MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES

Purity:≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 106 units/mg.

Calculated Molecular Weight:26.5 kDa

Accession Number:P05113

Gene ID:3567

Country Of Origin: USA

Not for human use.