SiliaBond Carbonate (CO3) (R66030B)

SiliaBond^®Carbonate (Si–CO₃) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.

SiliaBondCarbonate 在清除硼酸方面也非常有效：在室温下 1 小时后，在 DCM 中加入一当量的苯硼酸可去除 99%。Si-CO₃可以在室温下使用4当量定量游离碱盐酸盐麻黄碱（通过^{1 H NMR确定100％收率）两小时}