EPTOMICS代理Atg12 （ATG12） antibody Eptomics公司抗体供应商
Rabbit Monoclonal Antibody
Description
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. Atg12 is the human homolog of a yeast protein involved in autophagy （1）. It is essential for Atg12 conjugation, and the ATG12-ATG5 conjugate is necessary to form autophagic vesicles （2）. The E3-like activity of the Atg12-Atg5 conjugate potentiates the formation of Atg8-PE; making the autophagic pathway analogous to ubiquitin-like pathways where an E3 conjugation ligase is required （3）.
Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:1,000-10,000IHC: 1:50-100ICC: 1:100-250IP: 1:10-100FC: 1:10-100
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis
Products Data
| | |
| Western blot analysis on （A） THP-1, （B） HepG2, （C） Raji, and （D） fetal kidney lysates using anti-Atg12 RabMAb （cat. #3473-1）. | Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Atg12 RabMAb （cat. #3473-1）. | Western blot analysis on （A） Atg12 transfected 293T and （B） 293T lysates using anti-Atg12 RabMAb （cat. #3473-1）. |
Specificity
A synthetic peptide corresponding to residues in human Atg12 was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Alternative Names
ATG12 antibody, APG12 antibody, APG12L antibody, FBR93 antibody, HAPG12 antibody, Ubiquitin-like protein ATG12 antibody, Autophagy-related protein 12 antibody
Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.2. Phillips AR et al. Genetics. 2008 Mar;178（3）:1339-53.3. Williams RA et al. Autophagy. 2009 Feb;5（2）:159-72.
| Product Name | Catalog # |
|---|
| Goat Anti-Rabbit IgG （H+L） HRP | 3053-1 |
| Goat Anti-Rabbit IgG polymerized HRP | 3051-1 |
| Cell Lysis Buffer | 3500-1 |
| Goat Anti-Rabbit IgG HRP Antibody | 3056-1 |
| Goat Anti-Rabbit IgG DyLight® 405 | 3063-1 |
| Goat Anti-Rabbit IgG DyLight® 488 | 3064-1 |
| Goat Anti-Rabbit IgG DyLight® 550 | 3065-1 |
| Goat Anti-Rabbit IgG DyLight® 594 | 3066-1 |
| Goat Anti-Rabbit IgG DyLight® 633 | 3067-1 |
| Goat Anti-Rabbit IgG DyLight® 650 | 3068-1 |
EPTOMICS代理Atg12 （ATG12） antibody Eptomics公司抗体供应商
咨询和选购
©
金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://brandmillipore.cn/thread-47633.htm
QQ:1749072012