Anti-IL5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-IL5 Polyclonal Antibody品牌:solarbio | 货号:K005391P

英文名称Anti-IL5 Polyclonal Antibody
宿主Rabbit
别名EDF;IL-5;TRF
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量15kDa
Gene ID3567
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human IL5
性状液体
Public Immunogen RangeRecombinant protein of human IL5
Subcellular LocationsSecreted
Swiss ProtP05113
克隆类型 Polyclonal Antibody
背景资料This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

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