Anti-NDUFV1PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-NDUFV1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-NDUFV1 Polyclonal Antibody品牌：solarbio | 货号：K005622P

英文名称	Anti-NDUFV1 Polyclonal Antibody
宿主	Rabbit
别名	CI-51K;CI51KD;UQOR1
应用	WB IF
稀释比例	WB 1:500-2000. IF 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	51kDa
Gene ID	4723
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human NDUFV1
性状	液体
Public Immunogen Range	Recombinant protein of human NDUFV1
Subcellular Locations	Mitochondrion
Swiss Prot	P49821
克隆类型	Polyclonal Antibody
背景资料	The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson’s disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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