Anti-PDK3PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-PDK3PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-PDK3 Polyclonal Antibody品牌：solarbio | 货号：K005628P

英文名称	Anti-PDK3 Polyclonal Antibody
宿主	Rabbit
别名	CMTX6;GS1-358P8.4
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	47kDa
Gene ID	5165
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human PDK3
性状	液体
Public Immunogen Range	Recombinant protein of human PDK3
Subcellular Locations	Mitochondrion matrix
Swiss Prot	Q15120
克隆类型	Polyclonal Antibody
背景资料	The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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