Anti-RPSAPolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-RPSAPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-RPSA Polyclonal Antibody品牌：solarbio | 货号：K005986P

英文名称	Anti-RPSA Polyclonal Antibody
宿主	Rabbit
别名	37LRP;67LR;ICAS;LAMBR;LAMR1;LBP;LBP/p40;LRP;LRP/LR;NEM/1CHD4;SA;lamR;p40
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Mouse
蛋白分子量	33kDa
Gene ID	3921
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human RPSA
性状	液体
Public Immunogen Range	Recombinant protein of human RPSA
Subcellular Locations	Cell membrane Cytoplasm Nucleus
Swiss Prot	P08865
克隆类型	Polyclonal Antibody
背景资料	Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

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