Anti-MMP13PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-MMP13 Polyclonal Antibody品牌:solarbio | 货号:K106443P

英文名称Anti-MMP13 Polyclonal Antibody
宿主Rabbit
别名CLG3;MANDP1;MDST
应用WB
稀释比例WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量58kDa
Gene ID4322
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human MMP13
性状液体
Public Immunogen RangeA synthetic peptide of human MMP13
Subcellular LocationsSecreted extracellular matrix extracellular space
Swiss ProtP45452
克隆类型 Polyclonal Antibody
背景资料Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

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