Anti-CXCR4PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CXCR4 Polyclonal Antibody品牌:solarbio | 货号:K106446P

英文名称Anti-CXCR4 Polyclonal Antibody
宿主Rabbit
别名CD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS
应用WB
稀释比例WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量48kDa
Gene ID7852
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human CXCR4
性状液体
Public Immunogen RangeA synthetic peptide of human CXCR4
Subcellular LocationsCell junction Cell membrane Early endosome Late endosome Lysosome Multi-pass membrane protein
Swiss ProtP61073
克隆类型 Polyclonal Antibody
背景资料Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

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