Anti-ELAC2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ELAC2 Polyclonal Antibody品牌:solarbio | 货号:K005034P

英文名称Anti-ELAC2 Polyclonal Antibody
宿主Rabbit
别名COXPD17;ELC2;HPC2
应用WB IHC IF
稀释比例WB 1:500-2000. IHC 1:50-200. IF 1:50-100.
交叉反应 Human
蛋白分子量92kDa
Gene ID60528
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ELAC2
性状液体
Public Immunogen RangeRecombinant protein of human ELAC2
Subcellular LocationsMitochondrion Nucleus
Swiss ProtQ9BQ52
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

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