Anti-LCP1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-LCP1 Polyclonal Antibody品牌:solarbio | 货号:K004065P

英文名称Anti-LCP1 Polyclonal Antibody
宿主Rabbit
别名CP64;HEL-S-37;L-PLASTIN;LC64P;LPL;PLS2
应用WB IP
稀释比例WB 1:500-2000. IP 1:20-50.
交叉反应 Human Mouse
蛋白分子量70kDa
Gene ID3936
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human LCP1
性状液体
Public Immunogen RangeRecombinant protein of human LCP1
Subcellular LocationsCell junction Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein cytoskeleton ruffle membrane
Swiss ProtP13796
克隆类型 Polyclonal Antibody
背景资料Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

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