Anti-GSTM3PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-GSTM3 Polyclonal Antibody品牌:solarbio | 货号:K005387P

英文名称Anti-GSTM3 Polyclonal Antibody
宿主Rabbit
别名GST5;GSTB;GSTM3-3;GTM3
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量27kDa
Gene ID2947
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human GSTM3
性状液体
Public Immunogen RangeRecombinant protein of human GSTM3
Subcellular LocationsCytoplasm
Swiss ProtP21266
克隆类型 Polyclonal Antibody
背景资料Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual’s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

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