Anti-Phospho-p53-S46PolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
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Anti-Phospho-p53-S46 Polyclonal Antibody品牌：solarbio | 货号：K006218P| 英文名称 | Anti-Phospho-p53-S46 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BCC7;LFS1;P53;TRP53 |
| 应用 | WB IP |
| 稀释比例 | WB 1:1000-2000. IP 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 44kDa |
| Gene ID | 7157 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S46 of human TP53 |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S46 of human TP53 |
| Subcellular Locations | Cytoplasm Endoplasmic reticulum Mitochondrion matrix Nucleus PML body |
| Swiss Prot | P04637 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
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