Anti-MANFPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-MANF Polyclonal Antibody品牌:solarbio | 货号:K007651P

英文名称Anti-MANF Polyclonal Antibody
宿主Rabbit
别名ARP;ARMET
应用IHC
稀释比例IHC 1:100-300.
交叉反应 Human Mouse Rat
蛋白分子量21kDa
Gene ID7873
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human MANF
性状液体
Public Immunogen RangeA synthetic peptide of human MANF
Subcellular LocationsCytoplasm
Swiss ProtP55145
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

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