Anti-ERCC2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ERCC2 Polyclonal Antibody品牌:solarbio | 货号:K004100P

英文名称Anti-ERCC2 Polyclonal Antibody
宿主Rabbit
别名COFS2;EM9;TFIIH;TTD;TTD1;XPD
应用WB IF
稀释比例WB 1:500-2000. IF 1:50-100.
交叉反应 Human Mouse
蛋白分子量87kDa
Gene ID2068
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ERCC2
性状液体
Public Immunogen RangeRecombinant protein of human ERCC2
Subcellular LocationsCytoplasm Nucleus cytoskeleton spindle
Swiss ProtP18074
克隆类型 Polyclonal Antibody
背景资料The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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