Anti-PLATPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-PLAT Polyclonal Antibody品牌:solarbio | 货号:K004111P

英文名称Anti-PLAT Polyclonal Antibody
宿主Rabbit
别名T-PA;TPA
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量63kDa
Gene ID5327
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human PLAT
性状液体
Public Immunogen RangeRecombinant protein of human PLAT
Subcellular LocationsSecreted extracellular space
Swiss ProtP00750
克隆类型 Polyclonal Antibody
背景资料This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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