Anti-PSMD2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-PSMD2 Polyclonal Antibody品牌:solarbio | 货号:K008227P

英文名称Anti-PSMD2 Polyclonal Antibody
宿主Rabbit
别名S2;P97;Rpn1;TRAP2
应用WB
稀释比例WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量100kDa
Gene ID5708
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human PSMD2
性状液体
Public Immunogen RangeRecombinant protein of human PSMD2
Swiss ProtQ13200
克隆类型 Polyclonal Antibody
背景资料The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.

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