Anti-ACTN2PolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
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Anti-ACTN2 Polyclonal Antibody品牌：solarbio | 货号：K003686P| 英文名称 | Anti-ACTN2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CMD1AA;CMH23 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 104kDa |
| Gene ID | 88 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ACTN2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ACTN2 |
| Subcellular Locations | Cytoplasm Z line myofibril sarcomere |
| Swiss Prot | P35609 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. |
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