Anti-JARID2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-JARID2 Polyclonal Antibody品牌:solarbio | 货号:K006069P

英文名称Anti-JARID2 Polyclonal Antibody
宿主Rabbit
别名JMJ
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量139kDa
Gene ID3720
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human JARID2
性状液体
Public Immunogen RangeRecombinant protein of human JARID2
Subcellular LocationsNucleus
Swiss ProtQ92833
克隆类型 Polyclonal Antibody
背景资料This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

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