Anti-IMPDH2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-IMPDH2 Polyclonal Antibody品牌:solarbio | 货号:K007078P

英文名称Anti-IMPDH2 Polyclonal Antibody
宿主Rabbit
别名IMPD2;IMPDH-II
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量56kDa
Gene ID3615
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human IMPDH2
性状液体
Public Immunogen RangeRecombinant protein of human IMPDH2
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP12268
克隆类型 Polyclonal Antibody
背景资料This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5′-monophosphate into xanthine-5′-monophosphate, which is then converted into guanosine-5′-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

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