Anti-ACKR2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ACKR2 Polyclonal Antibody品牌:solarbio | 货号:K007999P

英文名称Anti-ACKR2 Polyclonal Antibody
宿主Rabbit
别名D6;hD6;CCR9;CCBP2;CCR10;CMKBR9
应用WB IHC
稀释比例WB 1:200-1000. IHC 1:30-150.
交叉反应 Human
蛋白分子量43kDa
Gene ID1238
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ACKR2
性状液体
Public Immunogen RangeA synthetic peptide of human ACKR2
Subcellular LocationsCytoplasm
Swiss ProtO00590
克隆类型 Polyclonal Antibody
背景资料This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

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