品牌: wanleibio 公司: 沈阳万类生物科技有限公司

货号： WL01992 抗体名： Cleaved caspase-3抗体 抗体英文名： Cleaved caspase-3 antibody 浓度： >1mg/ml 应用范围： WB,IHC 宿主： 兔 适应物种： H,M,R,T 标记物： 无 克隆性： 否 保存条件： -20℃ 形态： 液体 亚型： IgG 规格： 50μl(>50μg)

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产品货号WL01992产品名称cleaved Caspase-3 Antibody预测分子量Predicted band size: 20 kDaObserved band size: 17 kDa别名CASP3; CPP32; CPP32B; SCA-1浓度＞1 mg/ml免疫原合成Caspase-3多肽抗体来源兔特异性抗人,小鼠,大鼠，兔克隆类型多克隆抗体产品应用WB ;IHC成分亲和纯化抗体，20 mM PBS，150 mM NaCl，100 μg/ml BSA，50%甘油，NaN₃<0.02%保存条件-20℃保存背景资料This Caspase-3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP).

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