品牌: wanleibio 公司: 沈阳万类生物科技有限公司

货号： WL03667 保存条件： -20℃ 浓度： ＞1 mg/ml 应用范围： WB 形态： 液体 亚型： IgG 适应物种： H,M,R 宿主： 兔 标记物： 无 抗体名： CDKN2A/p19ARF 抗体 抗体英文名： CDKN2A/p19ARF antibody 克隆性： 否 规格： 50μl(>50μg)

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产品货号WL03667产品名称CDKN2A/p19ARF Antibody预测分子量Predicted band size: 19 kDaObserved band size: 23 kDa别名ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P19; cyclin-dependent kinase inhibitor 2A; cyclin dependent kinase inhibitor 2A浓度＞1 mg/ml免疫原合成CDKN2A/p19ARF多肽抗体来源兔特异性抗人、小鼠、大鼠克隆类型多克隆抗体产品应用WB成分亲和纯化抗体，20 mM PBS，150 mM NaCl，100 μg/ml BSA，50%甘油，NaN₃<0.02%保存条件-20℃保存背景资料CDKN2A, also known as cyclin-dependent kinase Inhibitor 2A, is ubiquitously expressed in many tissues and cell types. p19ARF activates the p53 tumor suppressor. Somatic mutations of CDKN2A are common in the majority of human cancers, with estimates that CDKN2A is the second most commonly inactivated gene in cancer after p53. p19ARF, which is unrelated to p16, arises from transcription of an alternative reading frame of the p16 gene. Like p16, p19ARF has been shown to induce cell cycle arrest. Mice lacking p19 ARF but expressing functional p16 have been shown to develop tumors early in life.

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